کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
735518 | 1461717 | 2016 | 7 صفحه PDF | دانلود رایگان |
• Surfaces with superhydrophobic and superhydrophilic properties are described.
• Peptide solution droplets are deposited on surfaces with defined wetting properties.
• Cross β-sheet formation is probed by X-ray diffraction and FTIR spectroscopy.
• Raster-scan imaging is performed by synchrotron radiation micro- and nanobeams.
Droplets with colloidal biological suspensions evaporating on substrates with defined wetting properties generate confined environments for initiating aggregation and self-assembly processes. We describe smart micro- and nanostructured surfaces, optimized for probing single droplets and residues by synchrotron radiation micro- and nanobeam diffraction techniques. Applications are presented for Ac-IVD and β-amyloid (1–42) peptides capable of forming cross-β sheet structures. Complementary synchrotron radiation FTIR microspectroscopy addresses secondary structure formation. The high synchrotron radiation source brilliance enables fast raster-scan experiments.
Journal: Optics and Lasers in Engineering - Volume 76, January 2016, Pages 57–63