کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
736806 | 893892 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Film bulk acoustic resonators for DNA and protein detection and investigation of in vitro bacterial S-layer formation
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
الکتروشیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Film bulk acoustic resonators for DNA and protein detection and investigation of in vitro bacterial S-layer formation Film bulk acoustic resonators for DNA and protein detection and investigation of in vitro bacterial S-layer formation](/preview/png/736806.png)
چکیده انگلیسی
We report investigations on the use of film bulk acoustic resonators for the label-free, multiplexed biosensing of DNA and proteins. The used acoustic resonators were operated in shear mode at about 800 MHz. From the measured changes of frequency and in dissipation, the mass and the viscoelasticity of biomolecular films formed at the top electrode of the device could be derived, respectively. A mass sensitivity of ∼2 kHz cm2/ng and a minimum detectable mass of ∼1 ng/cm2 were achieved. To demonstrate the highly sensitive detection of the time evolution of protein adsorption, the adsorption kinetics and recrystallisation of bacterial surface layer proteins on gold surfaces were investigated.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensors and Actuators A: Physical - Volume 156, Issue 1, November 2009, Pages 180–184
Journal: Sensors and Actuators A: Physical - Volume 156, Issue 1, November 2009, Pages 180–184
نویسندگان
Martin Nirschl, Anja Blüher, Christiane Erler, Beate Katzschner, Inger Vikholm-Lundin, Sanna Auer, Janos Vörös, Wolfgang Pompe, Matthias Schreiter, Michael Mertig,