Imine-functionalized, turn-on fluorophore for DCP

A monopyrene-imine derivative 1 is a highly selective and sensitive “turn-on” fluorogenic probe for diethyl chlorophosphate (DCP), a stimulant for organophosphorus nerve agents. Upon addition of DCP to a solution of 1, a phosphoramidate was formed which exhibited an enhanced fluorescence emission at 425 nm. When exposed to DCP in the vapor phase, 1 impregnated on silica gel showed a sky-blue fluorescence.