کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7503432 | 1486109 | 2018 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Brain substrates of early (4Â h) cigarette abstinence: Identification of treatment targets
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
Results show that as few as 4Â h of abstinence can reduce resting rCBF in multiple nodes of the brain's mesocorticolimbic network, disrupting neural processing. Identifying early withdrawal treatment targets has far-reaching implications, which include thwarting relapse proclivities. Results parallel those of the extant human literature and are in agreement with an extensive preclinical literature showing compromised mesolimbic dopaminergic function and impairments in reward function during nicotine withdrawal.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Drug and Alcohol Dependence - Volume 182, 1 January 2018, Pages 78-85
Journal: Drug and Alcohol Dependence - Volume 182, 1 January 2018, Pages 78-85
نویسندگان
Teresa R. Franklin, Kanchana Jagannathan, Nathan Hager, Zhuo Fang, Sihua Xu, Joyce Wong, Anna Rose Childress, John A. Detre, Hengyi Rao, Reagan Wetherill,