Poly-dopamine thin film for voltammetric sensing of atenolol

In this paper, a novel and highly sensitive atenolol sensor based on a poly-dopamine (PDA) is presented. PDA has been synthesized using a facile electro-deposition method. The polymer has been characterized with different techniques such as scanning electron microscopy, cyclic voltammetry, and electrochemical impedance spectroscopy. The glassy carbon modified with PDA has been applied for extraction and electrochemical sensing of atenolol. The extraction parameters such as pH, extraction time, and agitation rate were optimized. Differential pulse voltammetry has been used for quantitative determination of atenolol. The PDA thin film-based sensing platform exhibits high selectivity and sensitivity with a detection limit of 2.7 × 10−8 M. Determination of atenolol in real samples has been demonstrated. The results suggested that the PDA modification of electrodes may provide a new strategy for atenolol concentration determination in physiological solutions.

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