کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7543528 | 1489557 | 2018 | 22 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Optimal control of intervention strategies and cost effectiveness analysis for a Zika virus model
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
سیاست های بهداشت و سلامت عمومی
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چکیده انگلیسی
This paper presents an optimal control strategy and a cost effectiveness analysis for the Zika virus disease. A mathematical model for the transmission of the Zika virus is considered with four preventive measures as control, namely: the use of treated bednets, the use of condoms, a medical treatment of infected persons, and the use of indoor residual spray (IRS). We obtain the reproduction number R0 for the disease and carry out a stability analysis. We observe that the disease's free equilibrium state is stable when R0<1 but unstable when R0>1, which leads to a spread of the disease. We examine the implementation of various combinations of the possible control strategies in order to determine the most cost-effective one. Based on the computational results, we conclude that a strategy that consists of treated bednets, treatment of symptomatic infected humans and indoor residual spray is the most cost effective strategy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Operations Research for Health Care - Volume 18, September 2018, Pages 99-111
Journal: Operations Research for Health Care - Volume 18, September 2018, Pages 99-111
نویسندگان
Abdulfatai A. Momoh, Armin Fügenschuh,