کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7552307 | 1490510 | 2016 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Human genetics after the bomb: Archives, clinics, proving grounds and board rooms
ترجمه فارسی عنوان
ژنتیک انسانی پس از بمب: آرشیو، کلینیک ها، زمین های اثبات شده و اتاق های هیئت مدیره
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
پس از جنگ، ژنتیک انسانی، ژنومیکس، تابش، بمب اتمی، خطر،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم کشاورزی و بیولوژیک (عمومی)
چکیده انگلیسی
In this paper I track the history of post-1945 human genetics and genomics emphasizing the importance of ideas about risk to the scientific study and medical management of human heredity. Drawing on my own scholarship as it is refracted through important new work by other scholars both junior and senior, I explore how radiation risk and then later disease risk mattered to the development of genetics and genomics, particularly in the United States. In this context I excavate one of the central ironies of post-war human genetics: while studies of DNA as the origin and cause of diseases have been lavishly supported by public institutions and private investment around the world, the day-to-day labor of intensive clinical innovation has played a far more important role in the actual human experience of genetic disease and genetic risk for affected families. This has implications for the archival record, where clinical interactions are less readily accessible to historians. This paper then suggests that modern genomics grew out of radiation risk; that it was and remains a risk assessment science; that it is temporally embedded as a form of both prediction and historical reconstruction; and that it has become a big business focused more on risk and prediction (which can be readily marketed) than on effective clinical intervention.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences - Volume 55, February 2016, Pages 45-53
Journal: Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences - Volume 55, February 2016, Pages 45-53
نویسندگان
Susan Lindee,