Non-covalent complexes between single-stranded oligodeoxynucleotides and poly(ethylene imine)

The dominant polyplexes formed by pentadeoxynucleotides with poly(ethylene imine) 400 or 800 have 1:1 stoichiometry. Solution and intrinsic stabilities of these non-covalent complexes follow the same order, with thymine-rich nucleotides showing the highest binding affinities.