The combined effect of supplementary Cr(III) propionate complex and iron deficiency on the chromium and iron status in female rats

Fe deficiency significantly reduced the Fe content in the tissues. Simultaneously, Cr3 supplementation mitigated the symptoms of Fe deficiency. Fe deficiency increased TIBC and transferrin levels but reduced ferritin and most haematological parameters. However, simultaneous addition of high doses of Cr3 did not deepen these adverse changes. Our results show that the trend of changes in the Fe-Cr interaction depends on the content of these elements in the body.