Optimization and application of headspace liquid-phase microextraction coupled with gas chromatography-mass spectrometry for determination of furanic compounds in coffee using response surface methodology

► A simple method was proposed to determine of furanic compounds from coffee. ► The method is based on HS-SPME combined with GC-MS. ► The effective parameters in HS-LPME were optimized using RSM based on CCD. ► The absence of matrix effect using the HS-LPME has been demonstrated. ► The figures of merit for furans in coffee using the proposed method were perfect.