A sensitive method for extraction and determination of endocrine-disrupting compounds from wastewater using 10-ethyl-acridone-2-sulfonyl chloride as pre-column labeling reagent by high-performance liquid chromatography with fluorescence detection

► A sensitive method for determination of endocrine-disrupting compounds (EDCs). ► C18 SPE cartridges were applied to sample extraction and provided good results. ► Sensitivity was much higher than traditional HPLC method. ► Five EDCs were found in wastewater samples.