Pyrido[3,2-b][1,4]oxazine and pyrido[2,3-b][1,4]benzoxazine systems from tetrafluoropyridine derivatives

Pyrido[3,2-b][1,4]oxazine and pyrido[2,3-b][1,4]benzoxazine systems are synthesised by annelation reactions from highly fluorinated pyridine derivatives and nitrogen and oxygen centred difunctional nucleophiles.