Synthesis of fluorine-containing α-amino acids in enantiomerically pure form via homologation of Ni(II) complexes of glycine and alanine Schiff bases

- Comprehensive review of asymmetric synthesis of fluorine-containing amino acids via Ni(II) complex chemistry.
- Methodologically flexible approaches including: alkyl halide alkylations, aldol, Michael, Mannich addition reactions, deracemization and (S) to (R) interconversion.
- Particular emphasis is made on the ability of fluorine to control the stereochemical outcome of asymmetric reactions.