Chemical constituents from Acanthopanax brachypus

► Forty-six compounds were isolated and identified from the stem barks of Acanthopanax brachypus. ► The research results confirms that Acanthopanax senticosus and A. brachypus are closely related taxonomically. ► Twenty-two compounds were isolated for the first time from the genus Acanthopanax. ► Four stilbenes being obtained for the first time from the genus Acanthopanax has the chemotaxonomic significance.