Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation

Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 152, 25 May 2018, Pages 298-306

Qi Yan, Yuzhe Chen, Baiyou Tang, Qiang Xiao, Rong Qu, Linjiang Tong, Jian Liu, Jian Ding, Yi Chen, Ning Ding, Wenfu Tan, Hua Xie, Yingxia Li,