Keywords: مهار کننده های EGFR; Bevacizumab; Colorectal cancer; Efatutazone; EGFR inhibitors; Erlotinib; Maintenance; MGN1703; Treatment duration;
مقالات ISI مهار کننده های EGFR (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: مهار کننده های EGFR; EGFR inhibitors; Anti-tumor activity; Cell migration; Structure–activity relationship
Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation
Keywords: مهار کننده های EGFR; EGFR inhibitors; Pyrimidine derivatives; Mutant selective inhibitors; AZD9291; T790M;
Design, synthesis, antiproliferative activity and docking studies of quinazoline derivatives bearing 2,3-dihydro-indole or 1,2,3,4-tetrahydroquinoline as potential EGFR inhibitors
Keywords: مهار کننده های EGFR; Quinazoline derivatives; Synthesis; Antiproliferative activity; EGFR inhibitors;
Nuevos fármacos en oncologÃa: efectos secundarios cutáneos y su manejo
Keywords: مهار کننده های EGFR; Inhibidores de EGFR; Fármacos antiangiogénicos; Anticuerpos anti-PD-1; Terapia molecular dirigida; Efectos adversos cutáneos; EGFR inhibitors; Antiangiogenic drugs; Anti-PD-1 antibodies; Targeted molecular therapy; Adverse skin effects;
Hit discovery of 4-amino-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide: A novel EGFR inhibitor from a designed small library
Keywords: مهار کننده های EGFR; Antiproliferative hits; EGFR inhibitors; Phenotypic screening; Anticancer cell lines assay; Pyrimidine derivatives;
Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents
Keywords: مهار کننده های EGFR; MDR; BCR-ABL inhibitors; EGFR inhibitors; VEGFR inhibitors; Drug combinations; ABC; ATP binding cassette; ADME-tox; absorption, distribution, metabolism, excretion, toxicity; AKT; v-akt murine thymoma viral oncogene homolog; ALL; acute lymphoblastic leuke
Novel morpholin-3-one fused quinazoline derivatives as EGFR tyrosine kinase inhibitors
Keywords: مهار کننده های EGFR; EGFR inhibitors; NSCLC; Quinazoline; Molecular docking; Anti-cancer
Design, synthesis, and docking studies of afatinib analogs bearing cinnamamide moiety as potent EGFR inhibitors
Keywords: مهار کننده های EGFR; Afatinib; Cinnamamide; Synthesis; Docking; EGFR inhibitors; Antitumor activity
A decrease in D-dimer concentration and an occurrence of skin rash as iatrogenic events and complementary predictors of survival in lung cancer patients treated with EGFR tyrosine kinase inhibitors
Keywords: مهار کننده های EGFR; D-dimer; Skin rash; Progression free survival; Lung cancer; EGFR inhibitors; Overall survival
Discovery of new [1,4]dioxino[2,3-f]quinazoline-based inhibitors of EGFR including the T790M/L858R mutant
Keywords: مهار کننده های EGFR; EGFR inhibitors; Lung cancer; T790M/L858R mutation; Quinazoline
Recent advances in 4-aminoquinazoline based scaffold derivatives targeting EGFR kinases as anticancer agents
Keywords: مهار کننده های EGFR; Quinazolines; EGFR inhibitors; Protein kinases; Tyrosine kinase inhibitors
Toward discovery of mutant EGFR inhibitors; Design, synthesis and in vitro biological evaluation of potent 4-arylamino-6-ureido and thioureido-quinazoline derivatives
Keywords: مهار کننده های EGFR; EGFR inhibitors; Quinazolines; Urea derivatives; Synthesis; EGFR-Her2 dual inhibitors; EGFR L858R/T790 mutant; EGFR Del19/T790M mutant;
Papulopustular Acneiform Eruptions Resulting From Trastuzumab, a HER2 Inhibitor
Keywords: مهار کننده های EGFR; Acneiform; Breast cancer; Breast oncology; Cutaneous toxicities; Dermatologic adverse events; EGFR inhibitors;
Coexpression of receptor tyrosine kinase AXL and EGFR in human primary lung adenocarcinomas
Keywords: مهار کننده های EGFR; AXL; EGFR inhibitors; NSCLC; EGFR mutation
Sécurité de la réintroduction de l'erlotinib à faible posologie après un syndrome main-pied induit par l'erlotinib dans une tumeur de Pancoast-Tobias
Keywords: مهار کننده های EGFR; Syndrome main-pied; Erlotinib; Inhibiteurs de l'EGFR; Inhibiteurs du VEGF; Toxidermies; Hand-foot syndrome; Erlotinib; EGFR inhibitors; VEGF inhibitors; Cutaneous side-effects;
EGFR mutation specific immunohistochemistry is a useful adjunct which helps to identify false negative mutation testing in lung cancer
Keywords: مهار کننده های EGFR; EGFR immunohistochemistry; EGFR inhibitors; erlotinib; gefitininb; lung cancer;
Novel ruthenium complexes ligated with 4-anilinoquinazoline derivatives: Synthesis, characterisation and preliminary evaluation of biological activity
Keywords: مهار کننده های EGFR; Ruthenium complexes; EGFR inhibitors; Multi-targeting; Anticancer agents; MCF-7
Four-membered heterocycles-containing 4-anilino-quinazoline derivatives as epidermal growth factor receptor (EGFR) kinase inhibitors
Keywords: مهار کننده های EGFR; EGFR inhibitors; Anti-tumor agents; Anilinoquinazolines; Four-membered heterocycles;
Comparison of KRAS Genotype: Therascreen Assay vs. LNA-Mediated qPCR Clamping Assay
Keywords: مهار کننده های EGFR; Cetuximab; Colorectal cancer; EGFR inhibitors; KRAS; Mutation assay;
Sebaceous glands as the primary target of EGFR-inhibitors in the development of papulopustular eruption
Keywords: مهار کننده های EGFR; Sebaceous glands; EGFR inhibitors; Papulopustular eruption; l-Ascorbyl-2-phosphate;
EGF receptor inhibitors increase ErbB3 mRNA and protein levels in breast cancer cells
Keywords: مهار کننده های EGFR; EGF; epidermal growth factor; EGFR; EGF receptor; Erk; extracellular signal-regulated kinase; FAS; (TNF receptor superfamily, member 6); FoxO3a; forkhead box O3a; Ki-67; (antigen KI-67); MEK-1; MAPK/Erk kinase 1; PI3K; phosphatidylinositol 3-kinase; EGFR
Recommendations on management of EGFR inhibitor-induced skin toxicity: A systematic review
Keywords: مهار کننده های EGFR; EGFR inhibitors; Guideline; Prophylaxis; Skin toxicity
Targeted agents in non-small cell lung cancer (NSCLC): Clinical developments and rationale for the combination with thoracic radiotherapy
Keywords: مهار کننده های EGFR; Non-small cell lung cancer; Targeted agents; Chemoradiotherapy; EGFR inhibitors; Antiangiogenic agents; Phase I trials; Preclinical models; Radiotherapy; Combined modality treatment
Scaffold oriented synthesis. Part 4: Design, synthesis and biological evaluation of novel 5-substituted indazoles as potent and selective kinase inhibitors employing heterocycle forming and multicomponent reactions
Keywords: مهار کننده های EGFR; Kinase scaffolds; Kinase inhibitors; Gsk3β inhibitors; Rock2 inhibitors; Egfr inhibitors; Imidazopyrimidine; Imidazopyridines; Van Leusen reactions; MCR, multicomponent reactions
Tissue sampling in lung cancer: A review in light of the MERIT experience
Keywords: مهار کننده های EGFR; Non-small-cell lung cancer; Tumour sampling; Bronchoscopy; Pathology; Biomarkers; Molecular analyses; EGFR inhibitors
Molecular modeling based approach, design synthesis and cytotoxic activity of 7-chloro-4-(2,5-dioxo-4-substitutedarylidine) piperazinoquinoline a hybrid pharmacophore, targeting EGFR, Tyrosine Kinase
Keywords: مهار کننده های EGFR; 4-Arylidinepiperazinylquinoline; EGFR inhibitors; Anti-breast cancer activity; Hybrid pharmacophore approach
Predictive markers in the adjuvant therapy of non-small cell lung cancer
Keywords: مهار کننده های EGFR; NSCLC; Adjuvant therapy; Targeted therapy; Customized therapy; Chemotherapy; Predictive biomarkers; EGFR inhibitors;
A novel diffusion cell model for the in vitro assessment of transcutaneous breast cancer therapeutics: Effect of permeants on MCF-7 cells cultured within the receptor compartment
Keywords: مهار کننده های EGFR; Breast cancer; Topical drug delivery; 4-Hydroxytamoxifen; EGFR inhibitors; PD98059; LY294002; Eicosapentaenoic acid; Cyclopore track etched membrane; Franz diffusion cell; Skin; Composite model
Non-mucinous and mucinous subtypes of adenocarcinoma with bronchioloalveolar carcinoma features differ by biomarker expression and in the response to gefitinib
Keywords: مهار کننده های EGFR; Mucinous BAC; Non-mucinous BAC; Ras; EGFR; EGFR inhibitors
Quantifying the sensitivities of EGF receptor (EGFR) tyrosine kinase inhibitors in drug resistant non-small cell lung cancer (NSCLC) cells using hydrogel-based peptide array
Keywords: مهار کننده های EGFR; Peptide array; EGFR tyrosine kinase; Polyacrylamide; EGFR inhibitors; Acquired resistance
Drug interactions among the epidermal growth factor receptor inhibitors, other biologics and cytotoxic agents
Keywords: مهار کننده های EGFR; EGFR inhibitors; Combination regimen; Drug interaction; Pharmacokinetics; Pharmacodynamics; Drug sequenceABC, ATP binding cassette; AUC, area under the curve; CR, complete response; Cmax, maximum plasma concentration; EGFR, epidermal growth factor recepto
Triple-negative breast cancer: Molecular features, pathogenesis, treatment and current lines of research
Keywords: مهار کننده های EGFR; Breast cancer; Triple negative; Basal-like; Molecular features; Breast epithelium; Molecular targets; Platinum compounds; PARP inhibitors; EGFR inhibitors; Antiangiogenics
Novel therapeutics in combination with radiotherapy to improve cancer treatment: Rationale, mechanisms of action and clinical perspective
Keywords: مهار کننده های EGFR; Radiotherapy; Radiosensitizer; EGFR inhibitors; Angiogenesis inhibitors; PARP inhibitors; Apoptosis targeting agents; Tyrosine kinase inhibitors; Response prediction
Management of unfit older patients with advanced NSCLC
Keywords: مهار کننده های EGFR; Unfit elderly patients; NSCLC; Chemotherapy; EGFR inhibitors;
Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors
Keywords: مهار کننده های EGFR; 2,7-Diamino-thiazolo[4,5-d]pyrimidine analogues; Epidermal growth factor receptor tyrosine kinase inhibitors; EGFR inhibitors
High rate of severe radiation dermatitis during radiation therapy with concurrent cetuximab in head and neck cancer: Results of a survey in EORTC institutes
Keywords: مهار کننده های EGFR; Cetuximab; Radiotherapy; Erythema; Sequelae; Skin reaction; EGFR inhibitors; Radiation dermatitis; Head and neck cancer
Hydrogel-based protein array for quantifying epidermal growth factor receptor activity in cell lysates
Keywords: مهار کننده های EGFR; Protein array; EGFR tyrosine kinase; Polyacrylamide; EGFR inhibitors
Squamous cell carcinoma of the breast
Keywords: مهار کننده های EGFR; Squamous cell carcinoma; Breast cancer; Platin; EGFR inhibitors
Lung cancer and its management
Keywords: مهار کننده های EGFR; chemo-radiotherapy; EGFR inhibitors; lung cancer; non-small-cell lung cancer; multidisciplinary team; palliative care; platinum-based chemotherapy; screening; small-cell lung cancer; surgery
Clinical significance and treatment of skin rash from erlotinib in non-small cell lung cancer patients: Results of an Experts Panel Meeting
Keywords: مهار کننده های EGFR; Erlotinib; Skin rash; NSCLC; EGFR; EGFR inhibitors
Effets secondaires cutanés des nouvelles molécules anticancéreuses : focus sur les molécules ciblant les récepteurs tyrosine kinase et le récepteur à l'EGF
Keywords: مهار کننده های EGFR; Toxicité cutanée; Inhibiteurs d'EGFR; Inhibiteurs de tyrosine kinase multicible; Thérapies anti-angiogéniques; Cutaneous side effect; EGFR inhibitors; Multitarget tyrosine kinase inhibitors; Anti-angiogenic therapy;
Combined chemo-radiotherapy for locally advanced non-small cell lung cancer: Current status and future development
Keywords: مهار کننده های EGFR; Locally advanced NSCLC; Combined chemo-radiotherapy; EGFR inhibitors; Angiogenesis inhibitors
Novel targets in gastric and esophageal cancer
Keywords: مهار کننده های EGFR; Targeted therapies; EGFR inhibitors; Angiogenesis inhibitors; Gastric cancer; Esophageal cancer
The complexity of targeting EGFR signalling in cancer: From expression to turnover
Keywords: مهار کننده های EGFR; Cancer; EGFR; Cell signalling; Trafficking; Turnover; EGFR inhibitors
Nonclassical Retinoids and Lung Carcinogenesis
Keywords: مهار کننده های EGFR; Bexarotene; Combination therapy; EGFR inhibitors; Rexinoids; Targeted therapy;