Sécurité de la réintroduction de l'erlotinib à faible posologie après un syndrome main-pied induit par l'erlotinib dans une tumeur de Pancoast-Tobias

We describe what is to our knowledge, the third case of erlotinib-induced HFS, a new secondary undesirable skin pathology for which, currently, exist few direct causal explanations or drug monitoring. This observation highlights the importance of broadening our knowledge of the exact mechanisms linking EGFR-TKI to the appearance of HFS in order to optimize treatment.