کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7802371 | 1501159 | 2012 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and pharmacological evaluation of pyrazolo[4,3-c]cinnoline derivatives as potential anti-inflammatory and antibacterial agents
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and pharmacological evaluation of pyrazolo[4,3-c]cinnoline derivatives as potential anti-inflammatory and antibacterial agents Synthesis and pharmacological evaluation of pyrazolo[4,3-c]cinnoline derivatives as potential anti-inflammatory and antibacterial agents](/preview/png/7802371.png)
چکیده انگلیسی
⺠A series of pyrazolo[4,3-c]cinnoline derivatives were synthesized. ⺠Characterized by IR, 1H NMR, 13C NMR, and DART-MASS technique. ⺠Anti-inflammatory, ulcerogenic, lipid peroxidation, COX-2 inhibition and antibacterial studies were performed. ⺠Compounds 4d and 4l showed excellent protection against inflammation. ⺠Compound 4b emerged as a potential dual anti-inflammatory-antibacterial agent.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 57, November 2012, Pages 176-184
Journal: European Journal of Medicinal Chemistry - Volume 57, November 2012, Pages 176-184
نویسندگان
Rajiv Kumar Tonk, Sandhya Bawa, Gita Chawla, Girdhar Singh Deora, Suresh Kumar, Vandana Rathore, Naveen Mulakayala, Azad Rajaram, Arunasree M. Kalle, Obaid Afzal,