Keywords: مهارکننده های COX-2; Angiogenesis; Colorectal cancer; COX-2 inhibitors; NSAI drugs;
مقالات ISI مهارکننده های COX-2 (ترجمه نشده)
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Keywords: مهارکننده های COX-2; Anti-inflammatory; COX-2 inhibitors; COX-1/COX-2 inhibition; Cyclocoumarol; Cyclooxygenase; Docking study;
Keywords: مهارکننده های COX-2; Acute toxicity study; Anti-inflammatory agents; COX-2 inhibitors; Gastro intestinal safety study; GUSAR; Molecular modelling;
Keywords: مهارکننده های COX-2; Confounding by indication; COX-2 inhibitors; German Pharmacoepidemiological Research Database; Instrumental variables; Physician's preference; Two-stage least squares;
Keywords: مهارکننده های COX-2; 1,5-Disubstituted tetrazoles; COX-2 inhibitors; COX-1 inhibitors; Molecular docking; Structure-activity relationship; Methylsulfonyl; Aminosulfonyl;
Keywords: مهارکننده های COX-2; preemptive analgesia; postoperative pain control; nonsteroidal anti-inflammatory drugs; NSAIDs; cyclooxygenase-2 inhibitors; COX-2 inhibitors; gabapentin;
Keywords: مهارکننده های COX-2; ankylosing spondylitis; COX-2 inhibitors; musculoskeletal system; nonsteroidal anti-inflammatory drugs
Role of cyclooxygenase-2 inhibitors in the survival outcome of colorectal cancer patients: AÂ population-based cohort study
Keywords: مهارکننده های COX-2; Colorectal cancer; COX-2 inhibitors; Overall survival; Mortality; Population-based study;
Anti-inflammatory and antioxidant potential of Guaianolide isolated from Cyathocline purpurea: Role of COX-2 inhibition
Keywords: مهارکننده های COX-2; 6α-hydroxy-4 [14], 10 [15]-guainadien-8α, 12-olide; Anti-inflammatory; Antioxidant; COX-2 inhibitors; Cyathocline purpurea; Molecular docking; CMC; carboxymethyl cellulose; COX-2; cyclooxygenase-2; CP; Cyathocline purpurea Buch-Ham ex D.; DPPH; 1, 1-dip
Anti-inflammatory, analgesic and COX-2 inhibitory activity of novel thiadiazoles in irradiated rats
Keywords: مهارکننده های COX-2; Thiadiazoles; COX-2 inhibitors; Anti-inflammatory; Analgesic; Toxicological studies; Irradiated rats; Docking;
Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities
Keywords: مهارکننده های COX-2; Indomethacin; Tetrahydrocarbazoles; COX-2 inhibitors; Molecular docking; PGE2; GDYDRQVQNPLRSD-UHFFFAOYSA-N; KWEQQTKSVSFAKU-UHFFFAOYSA-N; BLHFRERRAVRFPX-UHFFFAOYSA-N; NYNZAMINEWHYNQ-UHFFFAOYSA-N; CEOWGNHGKRXAKI-UHFFFAOYSA-N; CKMGIAVCGSOXAT-UHFFFAOYSA-N; QK
Synthesis, anti-inflammatory, cyclooxygenases inhibitions assays and histopathological study of poly-substituted 1,3,5-triazines: Confirmation of regiospecific pyrazole cyclization by HMBC
Keywords: مهارکننده های COX-2; S-Triazines; COX-2 inhibitors; Anti-inflammatory activity; Enaminone; HMBC; Histopathology;
FDA labeling of NSAIDs: Review of nonsteroidal anti-inflammatory drugs in cardiovascular disease
Keywords: مهارکننده های COX-2; Nonsteroidal anti-inflammatory drugs; Cardiovascular disease; Coronary artery disease; Cardiovascular risk; Rheumatologic disease; COX-2 inhibitors; Nonselective NSAIDs;
Quantitative structure-activity relationship based modeling of substituted indole Schiff bases as inhibitor of COX-2
Keywords: مهارکننده های COX-2; COX-2 inhibitors; Physicochemical parameters; QSAR;
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity
Keywords: مهارکننده های COX-2; COX-2 inhibitors; 1,5-diarylpyrrole derivatives; Anti-inflammatory agents; Antinociceptive agents; Antiproliferative activity; Molecular modelling
Docking studies and the crystal structure of two tetrazole derivatives: 5-(4-chlorophenyl)-1-{4-(methylsulfonyl)phenyl}-1H-tetrazole and 4-{5-(4-methoxyphenyl)-1H-tetrazol-1-yl}benzenesulfonamide
Keywords: مهارکننده های COX-2; 1,5-diaryl tetrazoles; COX-2 inhibitors; (methylsulfonyl)phenyl; Molecular docking; (aminosulfonyl)phenyl; Crystal structure
Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: Anti-inflammatory and analgesic activities
Keywords: مهارکننده های COX-2; Phthalimides; COX-2 inhibitors; Anti-inflammatory activity; Analgesic activity; Molecular docking
Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors
Keywords: مهارکننده های COX-2; AA; arachidonic acid; CMC; carboxymethylcellulose; COX; cyclooxygenase; Coxibs; COX-2 selective inhibitors; Das; accuracies percentages; DIPA; diisopropylamine; DMAP; dimethylaminopyridine; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; EIA; enzyme
Antitumor effects of celecoxib in COX-2 expressing and non-expressing canine melanoma cell lines
Keywords: مهارکننده های COX-2; Antitumor effects; Canine melanoma; Celecoxib; COX-2 inhibitors
Effect of NSAIDS and COX-2 inhibitors on the incidence and severity of asbestos-induced malignant mesothelioma: Evidence from an animal model and a human cohort
Keywords: مهارکننده های COX-2; Asbestos-induced mesothelioma; Cancer prevention; Non-steroidal anti-inflammatory drugs; COX-2 Inhibitors; Mouse model; Patient cohort;
Y a-t-il une place pour les inhibiteurs de la COX-2 en péri-opératoire ?
Keywords: مهارکننده های COX-2; Douleur postopératoire; Anti-inflammatoire non stéroïdien; Inhibiteurs sélectifs des COX-2; NSAIDs; COX-2 inhibitors; Postoperative pain; Analgesics;
Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents
Keywords: مهارکننده های COX-2; Pyrazole; COX-2 inhibitors; Inflammation; Drug design; Molecular modeling
QSAR analysis of furanone derivatives as potential COX-2 inhibitors: kNN MFA approach
Keywords: مهارکننده های COX-2; QSAR; V-Life; Furanone derivatives; COX-2 inhibitors
Molecular design, synthesis and biological evaluation of cyclic imides bearing benzenesulfonamide fragment as potential COX-2 inhibitors. Part 2
Keywords: مهارکننده های COX-2; Cyclic imides; Benzenesulfonamide; COX-2 inhibitors; Anti-inflammatory activities; Molecular docking;
Synthesis and bioactivities of some new 1H-pyrazole derivatives containing an aryl sulfonate moiety
Keywords: مهارکننده های COX-2; Pyrazole; Enaminone; p-Toluene sulfonyl chloride; Anti-inflammatory activity; COX-2 inhibitors
Therapeutic Approach: The Importance of Controlling Prostatic Inflammation
Keywords: مهارکننده های COX-2; Benign prostatic hyperplasia; Inflammation; Nonsteroidal anti-inflammatory drugs; COX-2 inhibitors; Vitamin D receptor agonists; Hexanic extract of Serenoa repens
The State of the Art in Preventing Postthoracotomy Pain
Keywords: مهارکننده های COX-2; thoracotomy; postoperative pain; regional analgesia; opioids; NSAIDs; COX-2 inhibitors
Novel 5-substituted 1H-tetrazoles as cyclooxygenase-2 (COX-2) inhibitors
Keywords: مهارکننده های COX-2; Cyclooxygenase; COX-2 inhibitors; 5-Substituted 1H-tetrazoles
Synthesis and evaluation of fluorobenzoylated di- and tripeptides as inhibitors of cyclooxygenase-2 (COX-2)
Keywords: مهارکننده های COX-2; Cyclooxygenase; COX-2 inhibitors; Peptides; Molecular probes;
Synthesis and pharmacological evaluation of pyrazolo[4,3-c]cinnoline derivatives as potential anti-inflammatory and antibacterial agents
Keywords: مهارکننده های COX-2; Pyrazolo[4,3-c]cinnoline; Anti-inflammatory agent; COX-2 inhibitors; Ulcerogenic activity; Docking simulations; Antibacterial agent;
Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2
Keywords: مهارکننده های COX-2; Pyrazole; Pyrazoline; Synthesis; COX-2 inhibitors; Anti-inflammatory; Molecular modeling
Synthesis and evaluation of 1,5-diaryl-substituted tetrazoles as novel selective cyclooxygenase-2 (COX-2) inhibitors
Keywords: مهارکننده های COX-2; Cyclooxygenase; COX-2 inhibitors; 1,5-Diaryl-tetrazoles
Effects of β-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro
Keywords: مهارکننده های COX-2; NZSTVWVZQPBFHU-HXFLIBJXSA-N; Harpagide; Harpagoside; Iridoids; Anti-inflammation; β-Glucosidase; COX-2 inhibitors;
Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study
Keywords: مهارکننده های COX-2; Cyclic imides; COX-2 inhibitors; Anti-inflammatory activities; Molecular docking
Review of the applications of different analytical techniques for coxibs research
Keywords: مهارکننده های COX-2; ACN; acetonitrile; AI; active ingredient; APCI; atmospheric pressure chemical ionization; BCG; bromocresol green; BCP; bromocresol purple; CD; cyclodextrin; CE; capillary electrophoresis; CMS; chlorophenylmethylsulfone; COX; cyclooxygenase; CZE; capillary
Sulfonamide derivatives of styrylheterocycles as a potent inhibitor of COX-2-mediated prostaglandin E2 production
Keywords: مهارکننده های COX-2; COX-2 inhibitors; Styrylheterocycles; PGE2 production; Structure–activity relationships
Selective regulation of aromatase expression for drug discovery
Keywords: مهارکننده های COX-2; Aromatase; COX-2 inhibitors; Sulfonanilides; SiRNA
A Phase III Randomized Trial of the Timing of Meloxicam With Iodine-125 Prostate Brachytherapy
Keywords: مهارکننده های COX-2; Prostate brachytherapy; Postimplant edema; Acute urinary retention; COX-2 inhibitors;
Antiangiogenic strategies in breast cancer management
Keywords: مهارکننده های COX-2; Breast cancer angiogenesis; Antiangiogenic agents; Monoclonal antibodies; Tyrosin kinase inhibitors; Metronomic chemotherapy; Bisphosphonates; Hormonal therapy; COX-2 inhibitors
Gastric and small bowel ileus after severe burn in rats: The effect of cyclooxygenase-2 inhibitors
Keywords: مهارکننده های COX-2; Burn; COX-2 inhibitors; Gastric emptying; Small bowel ileus
Heterotopic ossification in burns: Our experience and literature reviews
Keywords: مهارکننده های COX-2; Heterotopic ossification (HO); Burns; Radiation therapy (RT); Osteoprogenitor cells; COX-2 inhibitors; Continuous passive motion (CPM)
Tedanol: A potent anti-inflammatory ent-pimarane diterpene from the Caribbean Sponge Tedania ignis
Keywords: مهارکننده های COX-2; Diterpenes; Pimarane; Anti-inflammatory activity; COX-2 inhibitors; Marine sponges; Tedania ignis
Determination of two COX-2 inhibitors in serum and synovial fluid of patients with inflammatory arthritis by ultra performance liquid chromatography-inductively coupled plasma mass spectroscopy and quadrupole time-of-flight mass spectrometry
Keywords: مهارکننده های COX-2; COX-2 inhibitors; Celecoxib; Etoricoxib; Rheumatoid arthritis; Ultra performance liquid chromatography (UPLC); Inductively coupled plasma mass spectroscopy (ICPMS); Quadrupole time-of-flight mass spectrometry (Q-TOF);
Prevention of Nonsteroidal Anti-Inflammatory Drug-Induced Ulcer: Looking to the Future
Keywords: مهارکننده های COX-2; Aspirin; CINOD; Cyclooxygenase; COX-2 inhibitors; Hydrogen sulfide; Naproxen; Nitric oxide;
2,3,5-Substituted tetrahydrofurans: COX-2 inhibitory activities of 5-hydroxymethyl-/carboxyl-2,3-diaryl-tetrahydro-furan-3-ols
Keywords: مهارکننده های COX-2; Cyclooxygenase-2; 2,3-Diaryl-tetrahydrofurans; In vitro studies; COX-2 inhibitors; QSAR
QSAR analysis of 1,3-diaryl-4,5,6,7-tetrahydro-2H-isoindole derivatives as selective COX-2 inhibitors
Keywords: مهارکننده های COX-2; QSAR; RSA; COX-2 inhibitors; HOMO; FH2OFH2O
The cyclooxygenase-2/prostaglandin E2 pathway is involved in the somatostatin-induced decrease of epileptiform bursting in the mouse hippocampus
Keywords: مهارکننده های COX-2; Neuropeptide signalling; Epilepsy; Prostaglandin E2; COX-2 inhibitors; Hippocampal slices; Electrophysiological recordings
Novel 2-(4-methylsulfonylphenyl)pyrimidine derivatives as highly potent and specific COX-2 inhibitors
Keywords: مهارکننده های COX-2; 2-(4-Methylsulfonylphenyl)pyrimidines; 2-(4-Sulfamoylphenyl)pyrimidines; COX-2 inhibitors
Aromatase and COX in breast cancer: Enzyme inhibitors and beyond
Keywords: مهارکننده های COX-2; Aromatase; Cyclooxygenase-2; Prostaglandin E2; NSAIDs; COX-2 inhibitors; siRNA; Sulfonanilides
Recent advances in nonopioid analgesics for acute pain management
Keywords: مهارکننده های COX-2; Adjuvants; Opioids; NSAIDs; COX-2 inhibitors; NMDA antagonists; Alpha-2 adrenergic agonists; Anticonvulsants; Postoperative pain