کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7802430 | 1501159 | 2012 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis, spectral characterization and biological evaluation of a novel series of 6-arylsubstituted-3-[2-(4-substitutedphenyl)propan-2-yl]-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis, spectral characterization and biological evaluation of a novel series of 6-arylsubstituted-3-[2-(4-substitutedphenyl)propan-2-yl]-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines Synthesis, spectral characterization and biological evaluation of a novel series of 6-arylsubstituted-3-[2-(4-substitutedphenyl)propan-2-yl]-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines](/preview/png/7802430.png)
چکیده انگلیسی
⺠A novel series of triazolothiadiazines were synthesized. ⺠Compounds were screened for their cytotoxicity using MTT assay. ⺠Compounds also tested for their anthelmintic & antimicrobial activities. ⺠7j was the most promising cytotoxic agent with IC50 value of 10.54 μM in MCF-7 cells.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 57, November 2012, Pages 407-416
Journal: European Journal of Medicinal Chemistry - Volume 57, November 2012, Pages 407-416
نویسندگان
Pushpan Puthiyapurayil, Boja Poojary, Chandrashekhar Chikkanna, Sunil Kumar Buridipad,