Synthesis and antimicrobial activity of amido linked pyrrolyl and pyrazolyl-oxazoles, thiazoles and imidazoles

► Oxazoles, thiazoles and imidazoles having amide and olefin moieties were synthesized. ► 1,3-Dipolar cycloaddition to olefin moiety. ► We have synthesized pyrrolyl and pyrazolyl-oxazoles, thiazoles and imidazoles. ► Chlorosubstituted imidazoles showed more antimicrobial activity.