Novel platinum(II) and palladium(II) complexes of thiosemicarbazones derived from 5-substitutedthiophene-2-carboxaldehydes and their antiviral and cytotoxic activities

► Some thiosemicarbazones and their Pt(II) and Pd(II) complexes were synthesized. ► All compounds were tested their in vitro antiviral and cytostatic/toxic activity. ► 1b exhibited some selective inhibition against HCMV. ► 4a showed significant cytostatic potency against HeLa cell culture.