کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7803307 1501181 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Discovery of a novel nitroimidazolyl-oxazolidinone hybrid with potent anti Gram-positive activity: Synthesis and antibacterial evaluation
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Discovery of a novel nitroimidazolyl-oxazolidinone hybrid with potent anti Gram-positive activity: Synthesis and antibacterial evaluation
چکیده انگلیسی
►Antibiotic resistance to Gram-positive pathogens is a major problem in hospitals. ►The oxazolidinones, e.g. linezolid, are a relatively new class of orally active, totally synthetic antibacterial agents active against Gram-positive bacteria. ►The synthesis and in vitro antibacterial activity of novel oxazolidinones containing a nitro-heteroaryl core with potent activity against Gram-positive bacteria have been described.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 46, Issue 1, January 2011, Pages 65-70
نویسندگان
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