Recent progress of in-flight separators and rare isotope beam production

New-generation in-flight separators are being developed worldwide, including the Super-FRS separator at the GSI Facility for Antiproton and Ion Research (FAIR), the ARIS separator at the Michigan State University (MSU) Facility for Rare Isotopes Beams (FRIB), and the BigRIPS separator at the RIKEN RI Beam Factory (RIBF), each of which is aimed at expanding the frontiers of rare isotope (RI) production and advancing experimental studies on exotic nuclei far from stability. Here, the recent progress of in-flight separators is reviewed, focusing on the advanced features of these three representative separators. The RI beam production that we have conducted using the BigRIPS separator at RIKEN RIBF is also outlined.