کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
810605 1469096 2015 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Quantification of in vitro wear of a synthetic meniscus implant using gravimetric and micro-CT measurements
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
Quantification of in vitro wear of a synthetic meniscus implant using gravimetric and micro-CT measurements
چکیده انگلیسی


• Long-term use of a synthetic polycarbonate-urethane meniscus implant was simulated.
• Wear was measured using gravimetric and volumetric methods.
• The implant material and wear debris were characterized using SEM and AFM.
• Mild damage consisting of abrasion was confined to the implant surface.
• The average gravimetric wear rate was 15–19 mg per million cycles.

A synthetic meniscus implant was recently developed for the treatment of patients with mild to moderate osteoarthritis with knee pain associated with medial joint overload. The implant is distinctively different from most orthopedic implants in its pliable construction, and non-anchored design, which enables implantation through a mini-arthrotomy without disruption to the bone, cartilage, and ligaments. Due to these features, it is important to show that the material and design can withstand knee joint conditions. This study evaluated the long-term performance of this device by simulating loading for a total of 5 million gait cycles (Mc), corresponding to approximately five years of service in-vivo. All five implants remained in good condition and did not dislodge from the joint space during the simulation. Mild abrasion was detected by electron microscopy, but µ-CT scans of the implants confirmed that the damage was confined to the superficial surfaces. The average gravimetric wear rate was 14.5 mg/Mc, whereas volumetric changes in reconstructed µ-CT scans point to an average wear rate of 15.76 mm3/Mc (18.8 mg/Mc). Particles isolated from the lubricant had average diameter of 15 µm. The wear performance of this polycarbonate-urethane meniscus implant concept under ISO-14243 loading conditions is encouraging.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Mechanical Behavior of Biomedical Materials - Volume 49, September 2015, Pages 310–320
نویسندگان
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