کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8160046 | 1524997 | 2018 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Estimation of physiological sources of nonlinearity in blood oxygenation level-dependent contrast signals
ترجمه فارسی عنوان
برآورد منابع فیزیولوژیکی غیر خطی در سیگنال های کنتراست وابسته به سطح اکسیژن خون
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
فیزیک ماده چگال
چکیده انگلیسی
Blood oxygenation level-dependent (BOLD) contrast appears through a variation in the transverse relaxation rate of magnetic resonance signals induced by neurovascular coupling and is known to have nonlinear characteristics along echo time (TE) due to the intra-vasculature. However, the physiological causes of this nonlinearity are unclear. We attempted to estimate the physiological information related to the nonlinearity of BOLD signals by using a two-compartment model. For this purpose, we used a multi-echo gradient-echo echo-planar imaging sequence and developed a computational method to estimate the physiological information from the TE-dependent BOLD signals. The results showed that the average chemical exchange time in the intra-vasculature varied during stimulation, which might be the essential source of the nonlinearity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Magnetic Resonance Imaging - Volume 46, February 2018, Pages 121-129
Journal: Magnetic Resonance Imaging - Volume 46, February 2018, Pages 121-129
نویسندگان
Daehun Kang, Yul-Wan Sung, Satoshi Shioiri,