Assessment of Interfraction Patient Setup for Head-and-Neck Cancer Intensity Modulated Radiation Therapy Using Multiple Computed Tomography-Based Image Guidance

Daily random setup errors and CTV-to-PTV margins for treatment of head-and-neck cancer were affected by imaging quality. Our data indicated that larger margins were associated with MVFBCT and MVCBCT, compared with smaller margins for KVCBCT. IGRT modalities with better image quality are encouraged in clinical practice.