Adding Ipsilateral V20 and V30 to Conventional Dosimetric Constraints Predicts Radiation Pneumonitis in Stage IIIA-B NSCLC Treated With Combined-Modality Therapy

The correlation between pneumonitis and dosimetric constraints has been validated. Adding V20ipsi and V30ipsi to the classical total lung constraints could reduce pulmonary toxicity in concurrent chemoradiation treatment. V20ipsi and V30ipsi are important if the V20 to the total lung, V30 to the total lung, and mean lung dose have not exceeded the constraints of 31%, 18%, and 20 Gy, respectively.