Tumor Delineation Based on Time-Activity Curve Differences Assessed With Dynamic Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography in Rectal Cancer Patients

Both automated SUV contouring and manual tumor delineation possibly incorrectly assign healthy tissue, showing flat TACs, as being malignant. On the other hand, in some cases the manually drawn tumor contours do not cover all voxels showing steep upward TACs, suspected to be malignant. Further research should be conducted to validate the possible superiority of tumor delineation based on dynamic PET analysis.