Prediction of radiation-induced changes in the lung after stereotactic body radiation therapy of non-small-cell lung cancer

Conclusion: The Dmean, V7, and V10 can be used to predict the risk of lung toxicity after SBRT treatment of non-small-cell lung cancer. Because of the lack of patients with low prescribed doses, however, the related uncertainty of this prediction is still relatively large. The Dmean, V7, and V10 are equally well suited. The additional investigated variables did not provide significant advantages. The lower part of the lung appears to be more radiosensitive than the upper.