Administered activity and metastatic cure probability during radioimmunotherapy of ovarian cancer in nude mice with 211At-MX35 F(ab′)2

Conclusion: As a significant increase in the therapeutic efficacy was observed between the activity levels of 50 and 100 kBq (TFF increase from 22% to 50%), the conclusion was that the MRA is ∼100 kBq 211At-MX35 F(ab′)2. MCP was most consistent with the TFF when assuming a diffusion depth of 30 μm of the mAbs in the tumors.