Clinical dose-volume histogram analysis in predicting radiation pneumonitis in Hodgkin's lymphoma

Conclusions: Despite relatively high V20 values in this study of HL patients, the incidence of RP was only 3%, lower compared with the lung cancer literature. We suggest the following clinically relevant parameters be considered in treatment plan assessment: a V20 greater than 36% and an MLD greater than 14 Gy, over and above which the risk of RTOG Grade 2 or greater RP would be considered clinically significant.