کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8262836 | 1534860 | 2016 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
What physical performance measures predict incident cognitive decline among intact older adults? A 4.4Â year follow up study
ترجمه فارسی عنوان
چه معیارهای عملکرد فیزیکی، پیش بینی کاهش حادثه شناختی در میان سالمندان سالم دست نخورده را پیش بینی می کند؟ یک مطالعه 4/8 ساله پیگیری
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کلمات کلیدی
عملکرد فیزیکی، قدرت عضلانی، شناخت،
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
سالمندی
چکیده انگلیسی
Reductions in physical performance, cognitive impairment (CI) and decline (CD), are common in older age, but few prospective cohort studies have considered the relationship between these domains. In this study we investigated whether reduced physical performance and low handgrip/lower limbs strength, could predict a higher incidence of CI/CD during a 4-year follow-up among a cohort of elderly individuals. From 3099 older community-dwelling individuals initially enrolled in the Progetto Veneto Anziani (PRO.V.A.) study, 1249 participants without CI at the baseline were included (mean age 72.2Â years, 59.5% females). Physical performance measures included the Short Physical Performance Battery (SPPB), 4Â m gait speed, chair stands time, leg extension and flexion, handgrip strength, and 6-Minute Walking Test (6MWT), categorized in gender-specific tertiles. CI was defined as a Mini-Mental State Examination (MMSE) score below 24; CD a decline of 3 or more points in the MMSE without CI. At baseline, participants developing CI during follow-up scored significantly worse across all physical performance measures compared to those that retained normal cognitive status. After adjusting for potential confounders, a significant trend for MMSE changes was noted for all physical performance tests, except for the SPPB and chair stands time. Multinomial logistic regression revealed that slow gait speed at baseline significantly predicted CD at follow up. Poor SPPB performance and slower gait speed predicted the onset of CI at the follow-up. In conclusion, slow walking speed appears to be the best independent predictor of poor cognitive status over a 4.4-year follow-up, while other items of SPPB were also significantly associated with CI.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Experimental Gerontology - Volume 81, August 2016, Pages 110-118
Journal: Experimental Gerontology - Volume 81, August 2016, Pages 110-118
نویسندگان
Nicola Veronese, Brendon Stubbs, Caterina Trevisan, Francesco Bolzetta, Marina De Rui, Marco Solmi, Leonardo Sartori, Estella Musacchio, Sabina Zambon, Egle Perissinotto, Gaetano Crepaldi, Enzo Manzato, Giuseppe Sergi,