کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8264297 | 1534886 | 2014 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
New advances in CMV and immunosenescence
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
سالمندی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: New advances in CMV and immunosenescence New advances in CMV and immunosenescence](/preview/png/8264297.png)
چکیده انگلیسی
Immunosenescence, defined as the age-associated dysregulation and dysfunction of the immune system, is characterized by impaired protective immunity and decreased efficacy of vaccines. An increasing number of immunological, clinical and epidemiological studies suggest that persistent Cytomegalovirus (CMV) infection is associated with accelerated aging of the immune system and with several age-related diseases. However, current evidence on whether and how human CMV (HCMV) infection is implicated in immunosenescence and in age-related diseases remains incomplete and many aspects of CMV involvement in immune aging remain controversial. The attendees of the 4th International Workshop on “CMV & Immunosenescence”, held in Parma, Italy, 25-27th March, 2013, presented and discussed data related to these open questions, which are reported in this commentary.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Experimental Gerontology - Volume 55, July 2014, Pages 54-62
Journal: Experimental Gerontology - Volume 55, July 2014, Pages 54-62
نویسندگان
Paolo Sansoni, Rosanna Vescovini, Francesco F. Fagnoni, Arne Akbar, Ramon Arens, Yen-Ling Chiu, Luka ÄiÄin-Å ain, Julie Dechanet-Merville, Evelyna Derhovanessian, Sara Ferrando-Martinez, Claudio Franceschi, Daniela Frasca, Tamas Fulöp, David Furman,