کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8298428 1536895 2018 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comprehensive cytotoxicity studies of superparamagnetic iron oxide nanoparticles
ترجمه فارسی عنوان
مطالعات جامع سمیت سلولی نانوذرات اکسید آهن فوق العاده پارامغناطیس
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
چکیده انگلیسی
Recently lots of efforts have been taken to develop superparamagnetic iron oxide nanoparticles (SPIONs) for biomedical applications. So it is utmost necessary to have in depth knowledge of the toxicity occurred by this material. This article is designed in such way that it covers all the associated toxicity issues of SPIONs. It mainly emphasis on toxicity occurred at different levels including cellular alterations in the form of damage to nucleic acids due to oxidative stress and altered cellular response. In addition focus is been devoted for in vitro and in vivo toxicity of SPIONs, so that a better therapeutics can be designed. At the end the time dependent nature of toxicity and its ultimate faith inside the body is being discussed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochemistry and Biophysics Reports - Volume 13, March 2018, Pages 63-72
نویسندگان
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