کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8348565 | 1541732 | 2013 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The interface of hypothalamic-pituitary-adrenocortical axis and circulating brain natriuretic peptide in prediction of cardiopulmonary performance during physical stress
ترجمه فارسی عنوان
رابط کاربری محور هیپوتالاموس-هیپوفیز-آدرنوکورتیک و پپتید ناتریتوری مونث مغزی در پیش بینی عملکرد قلب و ریه در طی استرس فیزیکی
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
ACTHSBPDBPCPETFFMBSA - BSANt-pro-BNP - NT-طرفدار BNPCardiopulmonary test - تست قلب و عروقCardiopulmonary exercise test - تست ورزش قلبی عروقیfat mass - توده چربیFat Free Mass - جرم آزاد چربیbody surface area - سطح بدنHeart rate - ضربان قلبdiastolic arterial blood pressure - فشار خون دیاستولیکsystolic arterial blood pressure - فشار خون سیستولیک شریانیStress axis - محور استرسHypothalamic–pituitary–adrenocortical axis - محور هیپوتالاموس-هیپوفیز-آدرنوکورتیکPeak oxygen consumption - مصرف اکسیژن قلهHPA - میلی بار یا هکتوپاسکالadrenocorticotropic hormone - هورمون adrenocorticotropichypothalamic–pituitary–adrenocortical - هیپوتالاموس-هیپوفیز-آدرنوکورتیکbody weight - وزن بدنbrain natriuretic peptide - پپتید ناتریورتیک مغزیcontrols - کنترل هاcortisol - کورتیزول
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
چکیده انگلیسی
Brain natriuretic peptide (NT-pro-BNP) was implicated in the regulation of hypothalamic-pituitary-adrenocortical (HPA) responses to psychological stressors. However, HPA axis activation in different physical stress models and its interface with NT-pro-BNP in the prediction of cardiopulmonary performance is unclear. Cardiopulmonary test on a treadmill was used to assess cardiopulmonary parameters in 16 elite male wrestlers (W), 21 water polo player (WP) and 20 sedentary age-matched subjects (C). Plasma levels of NT-pro-BNP, cortisol and adrenocorticotropic hormone (ACTH) were measured using immunoassay sandwich technique, radioimmunoassay and radioimmunometric techniques, respectively, 10 min before test (1), at beginning (2), at maximal effort (3), at 3rd min of recovery (4). In all groups, NT-pro-BNP decreased between 1 and 2; increased from 2 to 3; and remained unchanged until 4. ACTH increased from 1 to 4, whereas cortisol increased from 1 to 3 and stayed elevated at 4. In all groups together, ÎNT-pro-BNP2/1 predicted peak oxygen consumption (B = 37.40, r = 0.38, p = 0.007); cortisol at 3 predicted heart rate increase between 2 and 3 (r = â0.38,B = â0.06, p = 0.005); cortisol at 2 predicted peak carbon-dioxide output (B = 2.27, r = 0.35, p < 0.001); ÎACTH3/2 predicted peak ventilatory equivalent for carbon-dioxide (B = 0.03, r = 0.33, p = 0.003). The relation of cortisol at 1 with NT-pro-BNP at 1 and 3 was demonstrated using logistic function in all the participants together (for 1/cortisol at 1 B = 63.40, 58.52; r = 0.41, 0.34; p = 0.003, 0.013, respectively). ÎNT-pro-BNP2/1 linearly correlated with ÎACTH4/3 in WP and W (r = â0.45, â0.48; p = 0.04, 0.04, respectively). These results demonstrate for the first time that HPA axis and NT-pro-BNP interface in physical stress probably contribute to integrative regulation of cardiopulmonary performance.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Peptides - Volume 47, September 2013, Pages 85-93
Journal: Peptides - Volume 47, September 2013, Pages 85-93
نویسندگان
Dejana Popovic, Bojana Popovic, Bosiljka Plecas-Solarovic, Vesna PeÅ¡iÄ, Vidan Markovic, Stanimir Stojiljkovic, Vladan Vukcevic, Ivana Petrovic, Marko Banovic, Milan Petrovic, Bosiljka Vujisic-Tesic, Miodrag C. Ostojic, Arsen Ristic,