کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
838791 | 908369 | 2007 | 17 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Existence and uniqueness of the global solution for a mathematical model of the use of macrophages in tumor medicine
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موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Existence and uniqueness of the global solution for a mathematical model of the use of macrophages in tumor medicine Existence and uniqueness of the global solution for a mathematical model of the use of macrophages in tumor medicine](/preview/png/838791.png)
چکیده انگلیسی
In this paper we study a free boundary problem modelling of the use of macrophages as vehicles for drug delivery to hypoxic tumor sites. The model consists of five semi-linear parabolic partial differential equations. By applying the parabolic Schauder estimates and the Banach fixed point method, we prove that this system has a unique local classical solution. Using this result, parabolic LpLp estimates, the monotone method in the theory of reaction diffusion equations and the extension method, we further prove that if the tumor does not vanish at finite time then the solution exists for all t⩾0t⩾0.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nonlinear Analysis: Real World Applications - Volume 8, Issue 3, July 2007, Pages 922–938
Journal: Nonlinear Analysis: Real World Applications - Volume 8, Issue 3, July 2007, Pages 922–938
نویسندگان
Xuemei Wei, Shangbin Cui,