Molecular cloning and antifibrinolytic activity of a serine protease inhibitor from bumblebee (Bombus terrestris) venom

► Bumblebee venom serine protease inhibitor (Bt-KTI) is a plasmin inhibitor. ► Bt-KTI is a bumblebee venom Kunitz-type serine protease inhibitor. ► Bt-KTI consists of a 58-amino-acid mature peptide. ► Bt-KTI acts as an antifibrinolytic agent.