Comparative study of the cytolytic activity of snake venoms from African spitting cobras (Naja spp., Elapidae) and its neutralization by a polyspecific antivenom

► An in vitro assay to determine the cytolytic potency of venoms was established. ► The cytotoxic effect of five venoms from Naja spp. were comparatively assayed. ► The ability of an equine antivenom to neutralize these venoms was evaluated. ► Usefulness of this approach is discussed.