کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8428948 1546168 2018 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Toxicities associated with immunotherapies for hematologic malignancies
ترجمه فارسی عنوان
سمیت های مرتبط با ایمنوتراپی برای بدخیمی های هماتولوژیک
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی
Immunotherapy has generated tremendous hope for patients with cancer that is refractory to standard approaches. Hematologic malignancies have taken the lead in harnessing the most recent advances in cell-based immunotherapies, such as CAR T cells, and some patients have achieved durable remissions. However, these T-cell-engaging therapies are associated with a new set of toxicities which need to be managed by caretakers, oncologists, nurses, and healthcare staff. In this review we provide an overview of the toxicity of some of these revolutionary agents including bispecific T cell engagers, checkpoint inhibitors, chimeric antigen receptor T-cells.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Haematology - Volume 31, Issue 2, June 2018, Pages 158-165
نویسندگان
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