Impact of early tumour shrinkage and resection on outcomes in patients with wild-type RAS metastatic colorectal cancer

More patients receiving panitumumab + FOLFOX4 versus FOLFOX4 had ⩾30% or ⩾20% TS at week 8; PFS and OS were also improved with panitumumab + FOLFOX4. The clinical value of achieving early TS in mCRC warrants further investigation.