CD8+ and CD4+ tumour infiltrating lymphocytes in relation to human papillomavirus status and clinical outcome in tonsillar and base of tongue squamous cell carcinoma

In conclusion, in HPVDNA+ and/or HPVDNA+ p16INK4a+ tumours high CD8+ TIL counts indicated a better 3-year OS. This suggests that high CD8+ TIL counts together with HPVDNA+ or HPVDNA+ p16INK4a+ could be used when selecting patients for more individualised treatment.