کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8447338 1547186 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Antiangiogenic agents and endothelin antagonists in advanced castration resistant prostate cancer
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Antiangiogenic agents and endothelin antagonists in advanced castration resistant prostate cancer
چکیده انگلیسی
Despite multiple advances in prostate cancer therapy, treatment options for castration resistant disease are very limited. While data from recent studies are encouraging, there is no drug that has significantly improved results of standard chemotherapy. Some of the most consistent results are provided by antiangiogenic agents, showing high response rates and manageable toxicity. We describe some of the main therapeutic angiogenesis inhibitors in metastatic castration resistant prostate cancer. These agents include vascular endothelial growth factor inhibitors, tyrosine kinase inhibitors, antiangiogenic and inmunomodulatory agents and endothelin receptor antagonists.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Cancer - Volume 47, Issue 12, August 2011, Pages 1846-1851
نویسندگان
, , , ,