Assessment of the in vitro and in vivo genotoxic and antigenotoxic effects of pimaradienoic acid in mammalian cells

► The DPPH assay showed that pimaradienoic acid exerted no antioxidant activity. ► Pimaradienoic acid has no genotoxic effect by micronucleus test. ► Pimaradienoic acid significantly reduced the chromosome and DNA damage.