Genotoxicity of TiO2 anatase nanoparticles in B6C3F1 male mice evaluated using Pig-a and flow cytometric micronucleus assays

► TiO2-NPs can reach the mouse bone marrow via i.v. route. ► TiO2-NPs are capable of inducing cytotoxicity in mouse bone marrow. ► TiO2-NPs are not genotoxic with in vivo micronucleus assay. ► TiO2-NPs are not mutagenic with Pig-a mutation assay.