کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8458018 1548865 2018 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Intraductal carcinoma of the prostate: What we know and what we do not know
ترجمه فارسی عنوان
کارسینوم داخل دهانی پروستات: آنچه ما می دانیم و چیزی که ما نمی دانیم
کلمات کلیدی
کارسینوم داخل دهانی پروستات، پارامترهای تشخیصی تشخیص های افتراقی، وقوع، مرفولوژی، اهمیت بالینی،
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی
Intraductal carcinoma of the prostate (IDC-P) is a malignant, clonal proliferation of cells growing within the basement membrane-bound structures of the prostate. IDC-P is usually associated with unfavorable clinicopathologic parameters such as large tumor volume, high-grade Gleason score, extra prostatic extension and seminal vesicle invasion. Majority of laboratory and patient data suggest that IDC-P represents intraductal spread of invasive carcinoma, rather than a precursor lesion. Additionally, relationship of IDC-P and adjacent invasive carcinoma has been investigated in a series of molecular studies. The differential diagnosis of IDC-P from other lesions is critical for patient management. In this article, we summarize current literatures regarding what we know about IDC-P, including its pathological morphology, incidence, differential diagnosis, molecular features and clinical significance. In addition, we propose several issues that we currently do not know about IDC-P. Further research is needed to better understand the biological nature of IDC-P.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pathology - Research and Practice - Volume 214, Issue 5, May 2018, Pages 612-618
نویسندگان
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