کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8461 591 2010 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The biocompatability of mesoporous inorganic–organic hybrid resin films with ionic and hydrophilic characteristics
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
The biocompatability of mesoporous inorganic–organic hybrid resin films with ionic and hydrophilic characteristics
چکیده انگلیسی

New mesoporous silicate-titania resin systems hybridized with 4,5-dihydroxy-m-benzenedisulfonic acid and poly(ethylene glycol)-dimethacrylate component were developed. These inorganic-organic hybrid resins were found to reveal highly controlled ionic and hydrophilic surface with excellent durability and adhesion onto various substrates. The resin films revealed high resistance to nonspecific adsorption of fibrinogen and to adherence by several bacterial pathogens such as Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis and Enterococcus faecalis. Furthermore, excellent biocompatibility of the developed resins was proved by both HEp-2 cell adhesion in vitro and subcutaneous implantation in mice. The inorganic–organic hybrid resins are strongly promising for biomedical applications including biomedical devices and biosensors.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomaterials - Volume 31, Issue 9, March 2010, Pages 2517–2525
نویسندگان
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