Cancer-testis antigen, BORIS based vaccine delivered by dendritic cells is extremely effective against a very aggressive and highly metastatic mouse mammary carcinoma

► DC/mBORIS vaccine has therapeutic efficacy in a treatment setting. ► Vaccination increased the number of tumor-infiltrated effector T cells. ► Inhibited the growth of pre-existing, aggressive, nonimmunogenic 4T1 mammary carcinoma. ► Decreased the metastatic disease in the lungs.