Cycling in the nucleus: regulation of RNA 3′ processing and nuclear organization of replication-dependent histone genes

- Histone locus bodies coordinate assembly of transcription and 3′ processing complexes.
- Histone gene transcription induces chromatin changes that favor mRNA 3′ processing.
- Cyclic control of a histone processing factor that uses proteins of polyA machinery.
- U7 snRNP represses histone gene transcription outside of S phase.
- Links between histone gene expression, DNA damage, cell proliferation and diseases.