Utility of routine evaluation of sterility of cellular therapy products with or without extensive manipulation: Best practices and clinical significance

- Routine sterility testing improves best practices in the HSCT setting.
- Contamination of stem cell products has no significant impact on the outcome of HSCT.
- Use of antibiotics in media for expansion of ATMPs is advisable.
- Costs of sterility testing of ATMPs is high when performed in GMP-approved laboratory.